Etiologic agents are those microorganisms and microbial toxins that cause disease in humans and include bacteria, 
bacterial toxins, viruses, fungi, rickettsiae, protozoans, and parasites. These disease-causing microorganisms may also 
be referred to as infectious agents. Arthropods and other organisms that transmit pathogens to animals (including 
humans) are called vectors.
Etiologic agents, vectors, and materials containing etiologic agents are recognized as hazardous materials. Materials 
containing etiologic agents are regularly transported from one location to another by common land and air carriers. 
Materials containing etiologic agents must be appropriately packaged to prevent breakage or leakage in order to avoid 
exposure of the package handlers, transporters, and the general public to the package contents. Materials containing 
etiologic agents must be packaged, labeled, and transported in accordance with all applicable regulations. Material 
containing etiologic agents being imported into the United States must be accompanied by a U.S. Public Health Service 
importation permit.